2015-07-27
7月27日上午8时,布兰迪斯大学徐兵教授应我组组长王启刚教授的邀请,于化学馆120室,为我系师生进行了题为《Enzyme-Instructed Self-Assembly: A Multi-Step Process for Potential Cancer Therapy》的学术报告。与徐兵教授同行的还有其弟子杨志谋教授(南开大学生物活性材料教育部重点实验室),另外,值得一提的是,徐兵教授也是王启刚教授在香港科技大学攻读博士后期间的授业恩师。
报告伊始,徐兵教授就以美国的历史为例,用生动形象的语言阐述了“自组装”的概念,并以此为引,深入浅出地介绍了自组装水凝胶的历史发展以及展望。报告中,徐兵教授重点介绍了酶促自组装超分子水凝胶在癌症治疗中的研究成果以及应用潜力,并提出了其新的研究思路——在癌细胞外自组装形成纳米纤维网络以阻断细胞间的信息传递。报告最后,徐兵教授耐心解答了与会师生的提问,整个报告在热烈的掌声中圆满结束。
徐兵教授简介: 徐兵教授早年毕业于南京大学,他在南京大学获得学士、硕士学位之后去了美国。1996年在美国宾夕法尼亚大学(Universityof Pennsylvania)获得博士学位,1996~1997在美国麻省理工学院(Massachusetts Institute of Technology)从事博士后研究,但是随后又转移到哈佛大学(Harvard University,1997~2000)继续从事博士后研究。2000年8月,徐兵作为一名助理教授进入香港科技大学(Hong Kong University of Science & Technology),2006年元月被聘为副教授,2008年8月被聘为教授,同年9月他又以副教授的头衔进入美国布兰迪斯大学(Brandeis University) ,该大学是位于美国马赛诸塞州波士顿地区沃尔瑟姆镇的一所颇具实力的私立综合性大学,2009年11月,徐兵被聘任为教授。 徐兵博士曾经获得多个奖项,如2008年获得了人类前沿科学项目奖(Human Frontier ScienceProgram Award 2008)、2007年先后获得卓越讲师职务奖(DistinguishedLectureship Award 2007)、日本化学会亚洲国际研讨会奖(CSJ Asian International Symposium 2007)以及日本化学学会奖(Chemical Society of Japan 2007),2001年获得杜邦公司亚欧年轻研究者奖(DuPont Asian &European Young Investigator Award 2001),1997年获得美国国立卫生研究院博士后奖学金(NIH Postdoctoral Fellowship 1997)、1996年获得国际液晶学会格伦·布朗奖(Glenn Brown Award of International Liquid Crystal Society 1996)。目前徐兵教授是多个期刊的编委。他的研究领域包括材料化学、生物功能材料、高分子化学和表面化学、生物医学功能分子和纳米材料。他有上百篇学术论文在SCI收录期刊上发表,最近在Bioconjugate Chem. 杂志上发表的论文,《化学与工程新闻》(C&EN)周刊有专文介绍,谷歌学术搜索结果(被引频次>100)。
标题/作者 | 引用次数 | | 发表年份 | Multifunctional magnetic nanoparticles: design, synthesis, and biomedical applications J Gao, H Gu, B Xu Accounts of chemical research 42 (8), 1097-1107 | 692 |
| 2009 | Facile one-pot synthesis of bifunctional heterodimers of nanoparticles: a conjugate of quantum dot and magnetic nanoparticles H Gu, R Zheng, XX Zhang, B Xu Journal of the American Chemical Society 126 (18), 5664-5665 | 568 |
| 2004 | Dopamine as a robust anchor to immobilize functional molecules on the iron oxide shell of magnetic nanoparticles C Xu, K Xu, H Gu, R Zheng, H Liu, X Zhang, Z Guo, B Xu Journal of the American Chemical Society 126 (32), 9938-9939 | 527 |
| 2004 | Using biofunctional magnetic nanoparticles to capture vancomycin-resistant enterococci and other gram-positive bacteria at ultralow concentration H Gu, PL Ho, KWT Tsang, L Wang, B Xu Journal of the American Chemical Society 125 (51), 15702-15703 | 390 |
| 2003 | Heterodimers of nanoparticles: Formation at a liquid-liquid interface and particle-specific surface modification by functional molecules H Gu, Z Yang, J Gao, CK Chang, B Xu Journal of the American Chemical Society 127 (1), 34-35 | 374 |
| 2005 | Biofunctional magnetic nanoparticles for protein separation and pathogen detection H Gu, K Xu, C Xu, B Xu Chemical Communications, 941-949 | 350 |
| 2006 | Nitrilotriacetic acid-modified magnetic nanoparticles as a general agent to bind histidine-tagged proteins C Xu, K Xu, H Gu, X Zhong, Z Guo, R Zheng, X Zhang, B Xu Journal of the American Chemical Society 126 (11), 3392-3393 | 323 |
| 2004 | Enzymatic hydrogelation of small molecules Z Yang, G Liang, B Xu Accounts of chemical research 41 (2), 315-326 | 276 |
| 2008 | Supramolecular hydrogels respond to ligand-receptor interaction Y Zhang, H Gu, Z Yang, B Xu Journal of the American Chemical Society 125 (45), 13680-13681 | 256 |
| 2003 | Hydrophobic interaction and hydrogen bonding cooperatively confer a vancomycin hydrogel: a potential candidate for biomaterials B Xing, CW Yu, KH Chow, PL Ho, D Fu, B Xu Journal of the American Chemical Society 124 (50), 14846-14847 | 213 |
| 2002 | Enzymatic formation of supramolecular hydrogels Z Yang, H Gu, D Fu, P Gao, JK Lam, B Xu Advanced Materials 16 (16), 1440-1444 | 204 |
| 2004 | Presenting vancomycin on nanoparticles to enhance antimicrobial activities H Gu, PL Ho, E Tong, L Wang, B Xu Nano letters 3 (9), 1261-1263 | 204 |
| 2003 | FePt@ CoS2 yolk-shell nanocrystals as a potent agent to kill HeLa cells J Gao, G Liang, B Zhang, Y Kuang, X Zhang, B Xu Journal of the American Chemical Society 129 (5), 1428-1433 | 190 |
| 2007 | Multifunctional yolk− shell nanoparticles: A potential MRI contrast and anticancer agent J Gao, G Liang, JS Cheung, Y Pan, Y Kuang, F Zhao, B Zhang, X Zhang, ... Journal of the American Chemical Society 130 (35), 11828-11833 | 189 |
| 2008 | Using a kinase/phosphatase switch to regulate a supramolecular hydrogel and forming the supramolecular hydrogel in vivo Z Yang, G Liang, L Wang, B Xu Journal of the American Chemical Society 128 (9), 3038-3043 | 186 |
| 2006 | Magnetic‐Dipolar‐Interaction‐Induced Self‐Assembly Affords Wires of Hollow Nanocrystals of Cobalt Selenide J Gao, B Zhang, X Zhang, B Xu Angewandte Chemie 118 (8), 1242-1245 | 180 |
| 2006 | Molecular hydrogels of therapeutic agents F Zhao, ML Ma, B Xu Chemical Society Reviews 38 (4), 883-891 | 148 |
| 2009 | Intracellular spatial control of fluorescent magnetic nanoparticles J Gao, W Zhang, P Huang, B Zhang, X Zhang, B Xu Journal of the American Chemical Society 130 (12), 3710-3711 | 148 |
| 2008 | Design of coordination polymer gels as stable catalytic systems B Xing, MF Choi, B Xu Chemistry-a European Journal 8 (21), 5028-5032 | 138 |
| 2002 | Applications of nanomaterials inside cells J Gao, B Xu Nano Today 4 (1), 37-51 | 125 |
| 2009 |
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| Fluorescent magnetic nanocrystals by sequential addition of reagents in a one-pot reaction: a simple preparation for multifunctional nanostructures J Gao, B Zhang, Y Gao, Y Pan, X Zhang, B Xu Journal of the American Chemical Society 129 (39), 11928-11935 | 124 |
| 2007 | A biocompatible method of decorporation: bisphosphonate-modified magnetite nanoparticles to remove uranyl ions from blood L Wang, Z Yang, J Gao, K Xu, H Gu, B Zhang, X Zhang, B Xu Journal of the American Chemical Society 128 (41), 13358-13359 | 122 |
| 2006 | Using β-lactamase to trigger supramolecular hydrogelation Z Yang, PL Ho, G Liang, KH Chow, Q Wang, Y Cao, Z Guo, B Xu Journal of the American Chemical Society 129 (2), 266-267 | 117 |
| 2007 | Aromatic− Aromatic Interactions Induce the Self-Assembly of Pentapeptidic Derivatives in Water To Form Nanofibers and Supramolecular Hydrogels M Ma, Y Kuang, Y Gao, Y Zhang, P Gao, B Xu Journal of the American Chemical Society 132 (8), 2719-2728 | 111 |
| 2010 | Synthesis and cellular uptake of porphyrin decorated iron oxide nanoparticles—a potential candidate for bimodal anticancer therapy H Gu, K Xu, Z Yang, CK Chang, B Xu Chemical communications, 4270-4272 | 110 |
| 2005 | Chemical composition, crystal size and lattice structural changes after incorporation of strontium into biomimetic apatite ZY Li, WM Lam, C Yang, B Xu, GX Ni, SA Abbah, KMC Cheung, KDK Luk, ... Biomaterials 28 (7), 1452-1460 | 106 |
| 2007 |
——简介引自科学网诸平博客
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